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Obesity can reduce 13 yrs of your life
 

LONDON: Addicted to junk grub? Beware! Snacking on fast food and chomping in between meals can lead to weight gain and knock more than ten years off your life.

Yes, researchers in Britain have carried out a study and found that obesity is more dangerous than smoking as it can cut life expectancy by as much as 13 years.

"We must fight the notion that the current obesity epidemic arises from individual over indulgence or laziness alone. We live in a consumer society which encourages us to eat. We have a sedentary lifestyle.

"It's an environment which means that if we just behave normally we will become obese. We may only put on a bit of weight a day but there are 365 days in the year," according to lead researcher Professor David King.

Prof King, the British government's Chief Scientific Adviser, and his team of 250 scientists have published their study in a report, titled Foresight, on Wednesday.

The researchers have observed that being obese with a body mass index of more than 30 knocks nine years off a person's life while men with a BMI of more than 45 face nearly 13 years less life.

According to their findings, obesity -- which is now seen as "normal" -- not only leads to diabetes and heart disease but can also cause cancer, apart from various chronic health problems.

The researchers have also pointed out that the design of many towns and cities is based around the needs of the car and suggested more should be done to ensure that it's easier to walk to encourage residents to take more exercise.

"This will need a major culture change. The obesity issue is getting worse every year and we have not got much time to act," Prof King wrote.

 

Designing for Diabetics

Inspired by consumer gadgetry, medical-device makers are creating slick tools for insulin injections and readings

Tom Baldwin, a 43-year-old flight attendant, regularly wears two sleek gadgets strapped to his belt: an iPhone on one side and his Medtronic (MDT) MiniMed insulin pump on the other. Baldwin, diagnosed with diabetes more than 20 years ago, says passengers and co-workers rarely question why he's got two devices attached to his body. The pump is compact, with a large screen that displays his body's glucose levels in real time and a friendly user interface that features several control buttons with arrows on them. The device, says Baldwin, "looks like a pager."

"I used to be self-conscious about taking insulin shots or using my [earlier] insulin pumps," Baldwin says, referring to the cumbersome syringes and bulkier equipment he had to use. "But no one has ever asked me why I'm wearing this pump. The only people who notice are other diabetics on the flight, who can recognize that there's a tube sticking out of the pump—and they ask me where I got it, how it works."

A new study presented at the annual meeting of the European Association for the Study of Diabetes in Amsterdam Sept. 20, suggests that the design of a diabetes therapy device might affect a patient's experience with the disease. The Italian study examined quality of life among patients with type 1 diabetes. After surveying 1,341 patients, researchers found that diabetics using insulin pumps such as Baldwin's MiniMed experienced 70% less therapy-related dissatisfaction than patients using multiple injection therapy to manage their glucose levels. In other words, the user-friendly design of insulin pumps—which don't require needles and are therefore less complicated to use—can offer a more comfortable diabetes therapy experience.

Double-Digit Growth

The audience for diabetes-management tools is large—and growing. The Centers for Disease Control & Prevention estimates that there are 20.8 million American diabetics, about 7% of the U.S. population. According to the International Diabetes Federation's latest statistics, nearly 194 million adults around the world are diabetic; by 2025, according to estimates, this figure will reach 333 million. Palo Alto (Calif.) research and consulting firm Frost & Sullivan estimates that the U.S. market for traditional diabetes monitoring (blood testing equipment and strips that diabetics use to measure their glucose levels) tallied $3.53 billion last year, up 12% from 2005.

"In the last several years, we've seen low double-digit growth," says Mona Patel, director of Frost & Sullivan's medical research department. "Yes, there will be a saturation factor, but the number of diabetics keeps increasing—even among children." So, Patel says, the market for pediatric devices will grow, too.

Trendy-Looking

Medical-device manufacturers and industrial designers alike are increasingly using popular consumer electronics, from MP3 players to cell phones, as inspiration for easy-to-use and unobtrusive diabetes-management tools. The goal is to provide diabetics with equipment that fits as seamlessly into their lives as, say, an iPod, complete with an intuitive interface and a "cool" design factor that encourages patients to monitor their health and self-treat the disease. Just as Apple (AAPL) has used elegant design to competitive advantage, medical-device makers are hoping that trendy-looking diabetes devices will attract new customers and retain existing ones.

Dr. Alan Marcus, director of medical affairs at Medtronic, maker of Tom Baldwin's MiniMed pump, says that the company's research and development division is paying close attention to advances in consumer electronics design, from both a technological and user interface design standpoint. "It's our primary focus," he says. "We're actively moving in that direction."

In August, a specially equipped LG Electronics phone incorporating a glucose meter for diabetics received FDA approval. The GlucoPhone, created by Korean medical-device maker HealthPia, allows diabetics—after they prick a finger and take a blood sample—to insert a blood-test strip into the phone where a meter reads the results. Proprietary software allows the diabetic to send the blood data to a caregiver immediately.

And Bedford (Mass.) medical-device maker Insulet (PODD) has released OmniPod, designed in collaboration with design-strategy firm Continuum; it's on the market in selected areas of the U.S. The insulin management system consists of an infusion pump that attaches to the body via a thin tube and also synchs with a monitor that wirelessly communicates with the pump (the first of its kind). The device, a nominee for a prize at the INDEX: awards this year, won a Medical Design Excellence award, given by trade journal Medical Device & Diagnostic Industry, last year.

Introducing the insulin?

But large medical-device makers aren't the only companies paying attention to the market. Adaptive Path, a San Francisco user-experience design strategy consultancy best known for its Web-design work for companies including Intel (INTC), Crayola, and Wells Fargo (WFC), recently created a concept for a diabetes device called Charmr, which looks like a necklace charm. The concept was inspired by an open letter written by diabetic Amy Tenderich (author of the site Diabetes Mine) to Apple Chief Executive Steve Jobs.

"Most of these [diabetes] devices are clunky, make weird alarm sounds, are more or less hard to use, and burn quickly through batteries," wrote Tenderich. "In other words: their design doesn't hold a candle to the iPod." She called for Jobs to sponsor medical-device design contests, to enlist Apple design head Jonathan Ive to remake the contest winners into feasible products, and to fund an Apple medical design school. To date, Tenderich says Jobs has not responded to her letter.

Worthy Concept

After reading Tenderich's post, a group from Adaptive Path decided to respond; they applied their experience at designing user interfaces to creating a concept for a diabetes-management tool that might have the consumer appeal of an iPod. Their goal was not only to challenge themselves as designers but also to work on a humanitarian product to which they could apply their knowledge of user-centric interface design. "The language of the Web and the digital are moving into the physical," says Dan Saffer, an interaction designer at Adaptive Path who worked on the Charmr project. Saffer and his colleagues wanted to see if they could apply Web-style navigation elements and intuitive graphics to a medical device.

So this past summer the team spent nine weeks designing a two-part device consisting of a wearable pump and a controller that can be plugged into a flash drive to upload a diabetic's health data and transmit it to a caregiver. While Charmr exists only as computer renderings and in a faux-promotional video that's circulating on the Web, the idea, Saffer says, was to prompt other designers, consumer-electronics companies, and medical-device manufacturers to develop more user-friendly diabetes-tool designs.

But what's the value of a design concept if there's no contract to produce it? "It's kind of like a concept car or a couture dress—things that are experimental. Sure, it may not get made, but parts of the project can inspire others and eventually find their way to the mass market," says Shaffer. And there has been some early interest in Charmr. "We've been approached by diabetics who want to buy it, and we're talking with VCs in the medical-device world," says Saffer. "But we haven't been approached yet by Johnson & Johnson (JNJ). That would be nice."

Accuracy, After All, Trumps Design

Other companies see the value in developing innovative concepts. At this year's prestigious INDEX: awards (BusinessWeek, 9/10/07) in Copenhagen, Denmark, several nominees in the "body" category were diabetes-care concepts with consumer-electronics appeal.

Take, for instance, the prototype for a slick, minimalist insulin injection tool called the C-Cap, designed by Medicom, a division of Bang & Olufsen, the Danish manufacturer better known for high-end, gracefully designed audio and video equipment. C-Cap is shaped like a pen (an increasingly common metaphor in self-injection devices) and flashes a short green light every 24 hours to remind a diabetic to inject insulin; a long green flash signals the injection has registered. A red light flashes if the pen isn't used within an hour, sending a clear reminder.

Analysts agree that the design-centric approach to medical devices makes sense in terms of attracting patients and doctors. Of course, it's not just a product's surface appeal that determines which next-generation pumps and monitors will remain popular or boost a company's bottom line.

"Gadgetry that's consumer-like, with a cool factor, might be more appealing," says Frost & Sullivan's Patel. "But the one key feature is the accuracy of the device. This is important for doctors and patients: They need accurate results. I would say, in terms of looking for the most potentially successful devices, we should ask: 'Has the device been designed to minimize [blood glucose] sampling error?'"

Those devices that pass the test will prove that the beauty of an iPod-like pump or monitor for diabetics can be much more than skin deep.

Click here for the BusinessWeek slide show.

Jana is the Innovation Dept. editor for BusinessWeek.

 

 

Honey might help prevent ageing
15 Sep 2007, 1738 hrs IST,ANI

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LONDON: A new study has found that honey could be used to combat the effects of ageing, including memory decline and anxiety.

Studies conducted on mice found that those on diets including honey had better spatial memory and were less anxious.

Lynne Chepulis and Nicola Starkey of the
University of Waikato in Hamilton, New Zealand, raised rats on diets containing either ten per cent honey, eight per cent sucrose or no sugar at all for 12 months.

The rats were two months old at the start of the trial, and were assessed every three months using tests designed to measure anxiety and spatial memory.

The results showed that honey-fed rats spent almost twice as much time in the open sections of an 'assessment maze', which the researchers say suggests that they were less anxious.

They were also more likely to spend time in new sections of a Y-shaped maze, suggesting that they knew where they had been before and had better spatial memory.

"Diets sweetened with honey may be beneficial in decreasing anxiety and improving memory during ageing," stated Starkey.

The researchers propose that honey may boost memory due to its antioxidant properties, which help to prevent free radicals damaging cells in the body.

The findings were presented at the Association for the Study of Animal Behaviour meeting at
Newcastle University.

 

 

 

Blood test to spot cancer early
8 Sep 2007, 0444 hrs IST, IANS

 

LONDON: British scientists claim to have developed a blood test that offers the possibility of spotting cancer long before the symptoms appear.

The test successfully detected early signs of breast cancer in some women and the scientists hope the vital clues will help them to revolutionise cancer prevention by offering cheaper and less invasive screening techniques in the next ten years.

Cancer is a general term for about 100 diseases characterised by uncontrolled, abnormal growth of cells resulting in a mass or tumour that can invade and destroy healthy tissues.

The Southampton University research team studied blood samples collected from 11,000 women over the last 30 years, some of whom later developed cancer.

The researchers looked for biomarkers — proteins produced by cancer cells. They have seen significant biomarkers of breast cancer in the samples, reported the the Daily Mail.

"The quality of the samples has been the key but it is early days. Some of the ladies in the samples were healthy at the time but then went on to develop cancer. We are going back through these time capsules to look for things common in their blood that we can identify as a cancer fingerprint," Paul Townsend, who is leading the study, said

 

Lifestyle diseases to cut $200 bn from India's GDP by 2015: study.


By 2030, the cumulative loss in productive years for India is expected to be 17.9 million years, 940% more than the loss estimated in the US Jeetha D'Silva and C.H. Unnikrishnan Mumbai: Three major lifestyle diseases heart ailments, stroke and diabetes that have gripped India's productive population, are estimated to erode the country's gross national income by as much as $200 billion (Rs8,40,000 crore) by 2015, according to a recent study by consultancy firm PricewaterhouseCoopers.

The consulting firm estimates that India's loss, in terms of potentially productive years, due to deaths from cardiovascular diseases in people aged between 35 and 64 years is one of the highest in the world. By 2030, the cumulative loss in productive years for India is expected to be 17.9 million years, 940% more than the loss estimated in the US.

survey. "Fourteen years ago, when I started practicing in India, I used to see about one young (below 40 years) patient every two months, now I see a few every week," says Dr. Panda. "The situation has reached an alarming proportion." Dr Ramakanta Panda, a leading cardiac surgeon and vice-chairman of Asian Heart Institute in Mumbai, says he is not surprised by the findings of the PwC

The PwC report, titled Working Towards Wellness: An Indian Perspective, identifies chronic disease as a growing and costly threat to Indian corporations and their workers. "Deaths from chronic diseases would register a sharp increase from 3.78 million in 1990 to 7.63 million in 2020, accounting for 66.7% of all deaths," the report states. In 2005, heart disease, stroke and diabetes accounted for almost 53% of all deaths in India and 44% of disability-adjusted life years.

It goes on to say that the economic toll of chronic disease for developing and developed nations around the world is estimated at approximately 3% of the gross domestic product, globally.

In the study, PwC says it has examined the challenges faced by businesses as a consequence of the growing epidemic of chronic disease and found that approximately 2% of capital spent on workforce is lost to disability, absenteeism and diminished productivity from ailing employees who work below par due to chronic diseases. Collectively, these indirect costs are more than the direct medical claim costs that some employers incur.

study of 2005. The WHO data showed that the income loss due to lifestyle diseases among the productive population was $8.7 billion in India. The PwC estimate on the national income erosion by 2015 is based on WHO's 2005 statistics. The Indian survey is actually part of a global study initiated by the PwC Healthcare Research Institute, a research cell within PwC, for the World Economic Forum early this year. The report estimates the income loss due to chronic diseases in India with reference to a World Health Organization (WHO)

With India's young (productive) population estimated to be about 50% by 2015, chronic diseases affecting this section of the country's population take a toll on national productivity. WHO projects that by 2020, chronic diseases will account for almost three-quarters of all deaths worldwide, and that 71% of deaths due to cardiac disease, 75% of deaths due to stroke, and 70% of deaths due to diabetes will occur in developing countries. "On a global basis, 60% of the burden of chronic diseases will occur in developing countries. Indeed, cardiovascular diseases are even now more numerous in India and China than in all the economically developed countries in the world put together," a WHO study says.

From the drug industry perspective, the Indian cardiovascular drug market, which is estimated to be Rs2,500 crore a year, is currently 10% of the total Rs25,000 crore drug market.

The market for diabetes drugs is estimated to be worth over Rs1,000 crore. "These are the two fastest-growing segments with annual growth rates of 15% and 17%, respectively," says Kirit Gogri, a leading pharma analyst with Mumbai-based equity research firm, ASK Raymond James.

Some Indian corporations, especially large ones, are realizing the importance of employees' health and are beginning to invest in wellness programmes. "Indian multinationals in the information technology (IT) and IT-enabled services segments have been prominent in using the workplace to promote long-term health behavioural change to the measurable benefit of themselves, their employees and local communities," said Rajarshi Sengupta, executive director and leader of PwC's healthcare practice in India. "These companies run a number of wellness programmes covering employees from both the IT and business process outsourcing (BPO) sector to attract and retain talented, healthy employees."

Some of the programmes rolled out at IT companies such as Wipro and Infosys include nutrition consulting, health centres, medical camps, employee well-being events as well as initiatives to provide counselling for employees of the company. Hindustan Unilever Ltd, the largest maker of cosmetics and food products in India, also runs an employee wellness programme. "In cases of employees affected with chronic diseases such as hypertension, obesity, high cholesterol and diabetes, we continuously monitor their condition and proactively advise and provide medical assistance to better manage the condition," says Dr T. Rajgopal, vice-president, occupational health.

 

 

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